Utility of Intravenous Immune Globulin in Kidney Transplantation: Efficacy, Safety, and Cost Implications
نویسندگان
چکیده
منابع مشابه
Utility of intravenous immune globulin in kidney transplantation: efficacy, safety, and cost implications.
Intravenous immunoglobulin preparations (IVIG) are known to be effective in the treatment of various autoimmune and inflammatory disorders into their immunomodulatory, immunoregulatory, and anti-inflammatory properties. Recently, IVIG has been utilized in the management of highly sensitized patients awaiting renal transplantation. The mechanisms of suppression of panel reactive antibodies (PRA)...
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BACKGROUND.: We have shown that high-dose intravenous immune globulin (IVIG; 2 g/kg x2 doses)+rituximab (1 g x2 doses) was effective in lowering anti-human leukocyte antigen (HLA) antibodies and improving rates of transplantation. The aim of this report was to evaluate the efficacy of IVIG+rituximab on reduction of anti-HLA antibodies to a level that was permissive for living donor (LD) or dece...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2003
ISSN: 1600-6135
DOI: 10.1034/j.1600-6143.2003.00121.x